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The world’s insects are hurtling down the path to extinction, threatening a “catastrophic collapse of nature’s ecosystems”, according to the first global scientific review. Regular treatment is the key to keeping fleas at bay, but bathing your pet does nothing to prevent fleas. Today, pest control professionals often refer to fipronil as the “magic bullet” for killing termites. Ivermectin is an antiparasitic drug that works by dehydrating snake mites on contact. Fipronil is highly efficient at killing fleas and ticks on your dog. Some snakes will respond negatively to the drug. Fipronil … Once this product is administered on pets, all fleas get killed within a day’s time and ticks within 2 days. Topical treatment kills all life stages of fleas and ticks on dogs at least 8 weeks old and ranging from 6 to 22 pounds. Fipronil kills insects when they eat it or come in contact with it. Fipronil works by disrupting the normal function of the central nervous system in insects. Fipronil is more toxic to insects than people and pets because it is more likely to bind to insect nerve endings. Others have no problem with it. Prescription chemicals will be different in dogs and cats. Use Clear Plus Spot On with fipronil +s-methoprene for better protection. Frontline Plus is an OTC product that uses fipronil and (S)-methoprene to attack fleas and ticks at every life stage. The liquid mixture is absorbed through your cat's skin, killing attached fleas, ticks, and chewing lice while preventing future infestations within a one month period. The fipronil in Frontline Plus will kill the ticks in their younger stages, like the nymph stage, as well as when they are adults. One study involving 32 dogs compared the kill speeds of nitenpyram, selamectin, imidacloprid, and fipronil.3 Each treatment group comprised 8 dogs, and each dog was experimentally … A flea bath or dip is not necessary. For that, … Topical solutions kill fleas through contact with the product on the pet’s skin. Pyriproxyfen. Fipronil is useful in killing adult fleas and ticks while (S)-Methoprene contains an Insect Growth Regulator (IGR) that assists in abolishing the entire life cycle of fleas. How quickly does it kill fleas and ticks? Pour two to three drops of the mixture into the dog’s ear using a dropper. … Taurus SC contains 9.1% Fipronil, same active ingredient as Termidor SC. Itissafe for puppies and kittens older than 8weeks. Technicians or employees may poison, bait, trap and/or close off areas to pests. Frontline is a spot-on or topical treatment containing an insecticide called Fipronil. Be sure to clean your cat's environment as well. These attack adult fleas’ nervous systems. “When using chemicals, avoid products with imidacloprid and dinotefuran as they can be very toxic to children." The fact that an effectiv Benefits of apple cider vinegar for your pup s skin range from repelling fleas to soothing irritation. Pest control is the regulation or management of a species defined as a pest, a member of the animal kingdom that impacts adversely on human activities.The human response depends on the importance of the damage done and will range from tolerance, through deterrence and management, to attempts to completely eradicate the pest. The newer tick and flea medicine for cats, such as Bravecto and Nexgard, are not labeled for mites, but they do kill ear mites. The active ingredient Fipronil is fat soluble and as such is absorbed and stored in the oil glands ( sebaceous glands) of a pet. Similar to other flea treatments, this chewable tablet is given once per month and lasts for 30 days. Will Fipronil kill termites? Both products have low toxicity to mammals and pose little risk to pets or people. Fleas will start to die between 4 to 8 hours after application. Some reports suggest that this agent may be losing efficacy, at least against certain strains of fleas. The USEPA has determined fipronil to be safe for use on dogs and cats, with no harm to humans who handle these pets. Most of the time poisoning cases of fipronil occur in dogs and cats due to accidental ingestion of the product Frontline. In humans, poisoning is mainly due to accidental ingestions or suicidal attempt. Because vacuuming collects fleas but does not kill them, put some tape over the end of the vacuum cleaner hose to prevent fleas escaping from the bag, or transfer the bag to an outdoor … Cat Hair Loss From Flea Allergy Dermatitis CLINICAL RELEVANCE: Monthly imidacloprid application of 7.5 to 10 mg/kg will rapidly kill existing and reinfesting flea infestations on dogs and break the flea life cycle by killing adult fleas before egg production begins. Many of these agents are only available from a registered veterinarian. It works by affecting the central nervous system of the flea, … How is fipronil given? Paul B on Sep 9, 2020 BEST ANSWER: It can take a few hours for the product to kill ants, which allows for affected ants to spread the active ingredient to others … Spinosad has residual effect; it continues to kill adult fleas for 30 days before the next oral is required. Fipronil spreads over the cat or dog through body oils in about a day. Methoprene is a juvenile hormone (JH) analog which acts as a growth regulator when used as an insecticide.It is an amber-colored liquid with a faint fruity odor. … If you are seeing many fleas on the cats, then there are lots more in the environment. Juvenile growth hormones must be absent for a pupa to molt to an adult, so … After application, FRONTLINE Plus rapidly spreads to cover the entire surface of your dog’s body, localizing in the hair, on the skin and in the oil glands. Fipronil is used in a wide variety of pesticide products and in various formulations, These include foaming products, granular products, gel baits, and liquid concentrates. Kills fleas, … Some topical medications not only kill fleas and ticks, they also repel them. Frontline, marketed by Merial, effectively keeps fleas, ticks and lice off dogs and cats, when used as directed. Two studies were conducted to assess its speed of kill and knock-down effect on Ctenocephalides felis fleas. The insect’s brain and spinal cord are attacked by this chemical, ultimately leading to rapid death. Slow-acting stomach poison. The chemicals used to kill fleas may be hard on them, says Dr. Denise Genix, head of the infectious disease and immunology program at South Tampa Veterinary Clinic. Fipronil kills adult fleas and is typically formulated with an insect growth regulator. Common options include imidacloprid, dinotefuran, fipronil, and selamectin. If you … Flea5X Plus contains fipronil to quickly kill adult fleas, ticks and chewing lice on your pet. Get it on Chewy. What Factors Influence How Long Termite Treatments Last?Type of Termite. The type of termite can affect the length. Subterranean termites and drywood termites are the most common.Degree of Infestation. The degree of infestation is a major factor. The larger the termite colony, the longer it will take to eradicate.Home Environment. Your home’s set-up also contributes to the longevity of the treatment. ... What happens to the fleas after frontline? Once FRONTLINE Gold is applied, fipronil stores itself in the oil glands in your pet's skin. The active ingredient in FRONTLINE (fipronil) kills fleas by affecting their nervous system, making them hyperactive before dying. Some methods of eliminating fleas from cats and dogs are listed below. The active ingredient in FRONTLINE (fipronil) kills fleas by affecting their nervous system, making them hyperactive before dying. You can also … Firstect Plus is the generic equivalent to Frontline Plus® for dogs, puppies, cats and kittens 8 weeks and older, Firstect Plus contains Fipronil and (s)-methoprene – the active … Frontline is manufactured by Merial Animal Health and contains the active … Fipronil (Regent®, Icon®, Frontline®) is the only insecticide in this new class, introduced in 1990 and registered in the U.S. in 1996. How does FRONTLINE Gold kill fleas and ticks? Fipronil works to attack the fleas nervous system and sends them erratic, whereas the (s)-methoprene is a growth inhibitor to stop the fleas from developing further! What Kills Ticks Instantly? It gives a chance for treated insects to get back to the nest, where they poison others too. It doesn’t kill ticks, however, and dogs should not be allowed to lick the application site for at least 30 minutes to avoid potentially serious side effects. After application, FRONTLINE Plus rapidly spreads to cover … Limonene. It is not a repellent and … Citrus essential oils ingredient / Can be used near food. Unfortunately, a trap does not completely eliminate the fleas indoors – instead, it lets you determine and remove the hotbed of the disasters, kill many adult fleas, and then “finish off” the remaining ones with a vacuum, chemicals, and other means. Controlled efficacy of fipronil against C. felis and R. sanguineus ranged from 94% to 100% at these evaluation times. It will effectively kill adult fleas and ticks, but on its own won’t kill flea larvae and eggs. developed to control fleas, ticks, mosquitoes, sandflies and stable flies on dogs. It works by disrupting the central nervous system in insects and invertebrates (ticks are arachnids). 4. Some topical medications not only kill fleas and ticks, they also repel them. Fipronil NZ Suppliers. Find where to buy products from suppliers in NZ, including: distributors, manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods. Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, UK or the USA. Enlist the help of worms. Fipronil works to kill fleas and ticks currently on your pet, while the S-methoprene impairs reproduction. [4] FRONTLINE Plus® kills fleas, ticks & lice, plus stops flea eggs hatching in your home it is an advanced formula within the FRONTLINE® range of flea and tick treatments. Can fipronil affect birds, fish, or other wildlife Tests were done to find out if fipronil is toxic to fish and creatures in the water without … Frontline is a liquid medication that is applied to the skin of both dogs and cats to kill fleas and other parasites. Fipronil is an insecticide that kills the adult fleas. you breathe fipronil in; you swallow it. Advantage™ and Frontline™ provide 1- and 3-month protection from fleas, respectively. Fipronil is a broad use insecticide that belongs to the phenylpyrazole chemical family. Fipronil was first ... How does fipronil work Fipronil kills insects when they eat it or come in contact with it. … Steam clean carpets and upholstery if necessary. If you use fipronil for pets, to get rid of flea and ticks, they can be also exposed. Use a product that kills adult fleas, such as imidacloprid (Advantage™) or fipronil (Frontline™). Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family. Some … The Seresto 8-month flea and tick collar for large dogs provides continuous 8-month flea and tick protection. How does Frontline Plus work? Insect pesticides do not kill fleas in a flash – the flea needs to meet the fixing, retain it, and afterward begin to feel the impacts. Fipronil's specificity towards insects is believed … Flea5X Plus is a monthly topical flea and tick preventative for dogs and cats over 8 weeks of age. Hair shed from dogs for up to 2 weeks after topical treatment retains sufficient fipronil to kill dust mites (Dermatophagoides spp) coming in contact. Boric acid (dust) FIND THE BEST PRICE. These dying fleas often rise to the top of your pet’s … Fipronil is used in popular drops like Frontline and Pet Armor. S-methoprene is an Insect Growth Regulator (IGR), which affects flea eggs and flea larvae, preventing them from developing further. Then massage the dog’s ear gently. Those ingredients kill adult parasites and also their eggs and larvae. Frontline’s best puppy flea treatment comprises 2 tough killing ingredients, fipronil and (S)-methoprene. There are a number of chemicals and methods (pipettes are popular) to control flea infestations such as the application of lufenuron (Program), imidacloprid (Advantage), fipronil (Frontline), What does Fipronil kill? Controls infestations of chewing lice and sarcoptic mange mites. 4.2/5 (392 Views . 4.6/5 (56 Views . It also contains inert chemicals which bind these two chemicals together. Lufenuron (Program) is an insect growth regulator. Methoprene competes with endogenous insect develop hormones, preventing the breakdown of juvenile hormone, which when present prevents the development of eggs to larvae to pupae. Fipronil, in particular, sends adult fleas’ nervous systems into a hyperactive state, killing them in under 30 minutes. Imidacloprid is typically mixed with an oily carrier, so that when it is applied directly to the animal’s body, it spreads out over the body and collects in the hair follicles, where it … Flea5X Plus also contains (S)-methoprene, an insect growth regulator that kills flea eggs and larvae to help end the flea life cycle. Frontline kills fleas within 24 hours and helps prevent ticks. Fipronil works by killing parasites through contact, not via the bloodstream. These dying fleas often rise to the top of your … How old does my cat need to be/or weigh to use Onguard Plus Flea & Tick for Cats? A. FRONTLINE Gold has 3 secret weapons: fipronil, to take out adult fleas and ticks AND (S)-methoprene and pyriproxyfen to kill the next generation of flea eggs and larvae before they can develop into adult fleas. 3 Best Pesticides for Fleas. Without a functioning nervous system, the parasites die out. The active ingredient in FRONTLINE (fipronil) kills fleas by affecting their nervous system, making them hyperactive before dying. contains the active ingredients fipronil (100g/L) and (S)-methoprene (120g/L), both insecticides used in combination to treat and prevent infestation of fleas, ticks and biting lice in Cats. This study demonstrated that the speed of kill of fipronil, applied topically as a spot-on, was 100% against C. felis fleas on dogs within 12 to 18 hours after treatment and 100% against R. sanguineus ticks between 24 and 48 hours after treatment. Firstect Plus is the generic equivalent to Frontline Plus® for dogs, puppies, cats and kittens 8 weeks and older, Firstect Plus contains Fipronil and (s)-methoprene – the active ingredients used in Frontline Plus® for cats. Methoprene does not kill insects. surfaces, fipronil can be broken down by sunlight. Fipronil / To be sprayed on nests in the walls. The topical medication is used for flea and tick prevention, but studies find it is … Indeed, even once you are trying to kill any fleas in … In our research, NexGard was considered one of the best options to prevent fleas and ticks year-round, however does require a prescription from your vet in order … From here it is slowly released from the glands to the skin and fur. Mow your lawn. To combat the problem, be sure your pet is on year-round protection. Fipronil is used to control ants, beetles, cockroaches, fleas, ticks, termites, … Fipronil-containing products have proven an effective therapy to control fleas (Hutchinson et al., ... Fipronil Animal Safety Review Page 6 of 21 was associated with any topical reaction due to … Low-toxic insect killer / Use indoors, spray along the trails, down the cracks and shelters. Apply spray mist until animal’s hair is damp to thoroughly wet. What is Fipronil? Search and Destroy. In other settings, being slow acting is an advantage. Click to see full answer Also asked, how long does it take for imidacloprid to work? The Fipronil and S-methoprene in Frontline Plus have been developed to offer an all-round solution for pets. Fipronil disrupts the insect central nervous system by blocking the ligand-gated ion channel of the GABA A receptor and glutamate-gated chloride (GluCl) channels.This causes hyperexcitation of contaminated insects' nerves and muscles. How Does Frontline Gold Kill Fleas And Ticks. For the head and eye area, spray Frontline on a gloved hand and rub gently into your pet’s hair. Frontline should be effective on its own to treat fleas and ticks. The most common active chemicals in topical medications are: Fipronil: Fipronil works by attacking the nervous … Pesticides for fleas, no matter what form they come in, may have side effects. How long does it take for FRONTLINE Plus to kill fleas? The toxicity of fipronil and imidacloprid ranged from 0.11 to 0.40 ng/flea against adults, providing Resistance Ratios (RR 50) ranging from 0.11 to 2.21. We would like to show you a description here but the site won’t allow us. How much fipronil Can I give my … Taurus SC Insecticide with Fipronil. Broadline for cats contains … FRONTLINE Plus® Flea & Tick Treatment for small dogs 2-10kg and puppies over 8 weeks old. Active ingredients are Fipronil 9.80% and (S)-methoprene 11.80%. How does frontline flea and tick work Help protect your kitty from pests with Frontline Plus Flea & Tick Spot Treatment for Cats, over 1.5 lbs. Fleas can remain dormant in the wintertime, so it’s possible for an infestation to linger throughout the year. … The two tough pest control ingredients in this formula—fipronil and (S)-methoprene—work on killing both adult fleas, eggs and larvae, helping to prevent against further infestations. Does Cat Flea Treatment Kill Ear Mites? NexGard is the top rated prescription medication to kill and prevent fleas and ticks. Fipronil-containing products have proven an effective therapy to control fleas (Hutchinson et al., ... Fipronil Animal Safety Review Page 6 of 21 was associated with any topical reaction due to pre-existing skin conditions caused by the parasite. Termidor FOAM contains Fipronil, the same active ingredient as Termidor SC, in a ready-to-use foam that is labeled for termites and ants. The active ingredient in FRONTLINE (fipronil) kills fleas by affecting their nervous system, making them hyperactive before dying. There is a huge number of flea control products that can be used indoors, outdoor,s and on pets. Frontline kills fleas within 24 hours … They kill larvae is by paralyzing. What kind of insects does Frontline Plus kill? In dogs and cats, fipronil is available as a high-volume spray or a low-volume spot-on, with activity against ticks, fleas and ear mites. How Fipronil Works Frontline kills fleas and ticks on contact. For example when used to treat ants or cockroaches in the home. Fipronil was originally created to kill termites. Getting rid of fleas outside your home. Contains fipronil and (S)-methoprene, formulated to control fleas and ticks. Use Clear Plus Spot On with fipronil +s-methoprene for better protection. Contact with skin and eyes can happen while you are using fipronil. Some common flea- and tick-killing agents … Using flea treatment over-the-counter is particularly costly because millions do so every year. While many adults will wash away, the eggs will remain. Four active ingredients--imidacloprid selamectin, fipronil-(S)-methoprene, and metaflumizone--were tested to assess the speed of flea kill against existing flea infestations and subsequent … Take note that a single flea can lay almost 50 eggs a day. Fipronil, the active ingredient in Taurus, is known to be the best product on the market for termite control. In Frontline and Frontline Plus the fipronil is dispersed by the … Frontline does work, quite well. Taurus SC is a non-repellant insecticide labeled for termite treatments and … Stored … Frontline Plus Topical Flea & Tick for Dogs. Insecticides, both adulticides and insect growth regulators, are frequently used in chemical treatments. That classification includes fipronil, one of the active ingredients in Frontline Plus for cats. A. Upon … This … But, they go about the process a bit differently. These two active ingredients work on compromising the nervous system of fleas and ticks. It’s … Frontline(Fipronil & (S)- Methoprene) • After application on the skin between the shoulder blades, Frontline spreads inthe oils ofthe skin over the pet's body. Revolution : Its main ingredient is selamectin , which is said to kill not only fleas and some ticks, but also ear mites , as well as offering protection against heartworm . • The active ingredients are Fipronil and methoprene. Let’s see how to kill fleas in the house. Your Pet has Gotten a ‘hitch-hiker’ Flea. 38 Votes) Phantom is an indoor/outdoor termiticide and insecticide that kills termites, ants, cockroaches, and now bed bugs, through a powerful non-repellent active … fleas, ticks, termites, mole crickets, thrips, rootworms, weevils, and other insects. Frontline Plus is designed differently from most flea and tick control treatments, because it contains a combination of pesticides. Fipronil reacts with water to break down into smaller chemicals at a speed that increases as the water becomes less acidic. Outdoors, fleas can hide on the leaves of tall grass. Both products attack mites and kill them in minutes. It is not allowed anywhere near animals in . Frontline Gold has 3 secret weapons: fipronil, to take out adult fleas and ticks and -methoprene and pyriproxyfen to kill the next generation of flea eggs and larvae before they can develop into adult fleas. Fipronil is a white powder with a moldy odor. When fipronil in the water is exposed to sunlight it breaks down rapidly with a half-life of 4-12 hours. 3. What does a pest control company do? However, fipronil alone isn’t enough to fight against a horde of fleas and ticks. That is why S-methoprene comes to play. It also works well in eliminating those that transmit Lyme disease. Spinosad has residual effect; it continues to kill adult fleas for 30 days before the next oral is required. Along the way, fipronil was recognized as being lethal to a wide range of insects and pests, including fleas and ticks. Safe topical spot-on anti-adult flea formulations include imidacloprid, fipronil, dinotefuran, metalfumizone and selamectin. Frontline: Said to kill both fleas and ticks, Frontline uses a synthetic ingredient called fipronil, which may cause temporary sensitivity in the area of application. In a study, FRONTLINE Plus began killing fleas 4 hours after application.1 Another study showed that within 12 hours, Frontline … 1. Fipronil is the Frontline ingredient responsible for killing ticks and fleas on contact. Fipronil is a slow acting insecticide, which means it takes up to 48 hours to kill the fleas and ticks on your Labrador. Unlike oral flea and tick prevention products that require fleas and ticks to bite your pet to work, Seresto flea and tick collar for large dogs kills fleas and ticks through contact—no biting required. How much fipronil Can I give my cat? The chemicals used to kill fleas may be hard on them, says Dr. Denise Genix, head of the infectious disease and immunology program at South Tampa Veterinary Clinic. The most common active chemicals in topical medications are: Fipronil: Fipronil works by attacking the nervous system of the parasite to paralyze fleas and ticks to ultimately kill them. What are the active ingredients? Fipronil is used to Once ... 2. As an antiparasitic, Frontline does kill ticks, fleas and other pests that get in contact with it. As an antiparasitic, Frontline does kill ticks, fleas, and about all other pests. Lufenuron (Program) is an insect growth regulator. Pest control companies get rid of unwanted houseguests, like insects and rodents. The active ingredient Fipronil is fat-soluble and as such is absorbed and stored in the oil glands ( sebaceous glands) which are under the top layer of the skin (epidermis). Ticks may take 12 hours or longer to die and fall off and improvement in clinical signs should follow. Instead, it interferes with an insect’s life cycle and prevents it from reaching maturity or reproducing. Chemical-based formulas that contain Ivermectin or Fipronil work well. Administered monthly like the other topical treatments, Frontline should only be given to dogs 8 weeks or older. Does frontline plus kill ticks already on the dogFRONTLINE Plus contains fipronil and (S)-methoprene to kill existing adult fleas as well as flea eggs and larvae. BUY ON CHEWY. Other active ingredients like methoprene and pyriproxyfen inhibit eggs from developing,” explains Dr. Smith. Clean up your yard. The Combat’s roach killer bait is designed to attract and kill small roaches (like the German Roaches) in hours and prevent them from coming back for up to 12 months. Although Frontline Plus may kill 100 percent of the fleas immediately after you put it on your dog, its effectiveness will diminish throughout the month. A topical combination of fipronil + permethrin (Frontline Tri-Act®/Frontect®, Merial) has recently been developed to control fleas, ticks, mosquitoes, sandflies and stable … A. Summary: Frontline Plus kills fleas, ticks, and chewing lice in only 12 hours. You may swallow some product if you don’t wash your hands after using it. Termidor FOAM can be applied in and around residential and … It also contains ethanol, diethylene glycol monoethyl ether, polyvidone, polysorbate 80. Cat flea problems can occur in indoor and outdoor cats as people can bring fleas into the home. This treatment kills adult fleas, flea eggs, flea larvae, chewing lice, and ticks. These two ingredients kill both adult fleas and flea eggs, and their effects last for around one month. All cat flea collars should clearly list the active ingredients. This is an insecticide, and kills adult fleas and ticks. Fipronil should not be used when open skin wounds. They break down fairly quickly, so you’ll have to reapply. It disrupts the insect’s central nervous system and causes hyperexcitation of its nerves and muscles. These include products containing fipronil (Frontline, Effipro) Permethrin, Phosmet, fenthion, and selamectin (Revolution US, Advantage UK). Contains powerful insecticide formulation, Fipronil, which provide quick results. Advantage™ … As such, it is a good idea to keep the grass short by mowing regularly. Will kill an inaccessible colony within a few days. Fipronil is the most effective flea treatment available – as it affects the nervous system in fleas & ticks, killing fleas within 24 hours and ticks within 48 hours of contact. There are no parasitic products that are licensed to kill lice in dogs however several are known to be effective. FIND THE BEST PRICE. Imidacloprid – a systemic insecticide that acts as an insect neurotoxin to attack the central nervous system of sucking pests like fleas. Buy cedar chips. Effective for 30 days and safe for pups 8 weeks and older. Dog Tick Control with Fipronil Fipronil, a drug used in flea and tick control products and other insecticides, is an anti-parasitic agent that works by disrupting the central nervous system of insects. Frontline Plus is a licensed flea treatment that contains S-Methoprene and Fipronil. Most flea treatments just kill adult fleas, but fleas can continue to emerge for months after you think an infestation has ended. It is slowly released from the glands to the skin and fur. In Frontline Plus, Fipronil blocks the nerve receptors of the insects it encounters. It’s formulated with two active ingredients—fipronil and (S)-methoprene—to help disrupt the flea life cycle and inhibit future infestations. Active ingredients. Fipronil is the ingredient that affects adult fleas and ticks. Then, treat the mother with a prescription flea treatment that is safe for lactating mothers. [12, 13, 14] How to use yellow dock root extract for fleas in dogs ears: To one tablespoon of warm water add nine drops of yellow dock root extract. Frontline Plus contains a combination of two active ingredients, Fipronil and S-methoprene, this combination of treatments targets different … At week three or four, try giving your dog a Capstar pill. Squish the fleas or drop them into boiling water as you go to prevent them from re-infesting. It’s similar to you contracting a virus. Once Frontline Gold is applied, fipronil stores itself in the oil glands in your pet’s skin. Fipronil is applied topically to the skin or haircoat. Be sure to read the product label to make sure you are doing the … They consistently kill over 90 % of fleas and ticks on the dogs taking part , and keep them flea and tick free for at least four weeks . FRONTLINE Plus contains fipronil and (S)-methoprene to kill existing adult fleas as well as flea eggs and larvae. Frontline(Fipronil & (S)- Methoprene) • After application on the skin between the shoulder blades, Frontline spreads inthe oils ofthe skin over the pet's body. Fipronil works by damaging the nervous system of fleas and ticks while S-Methoprene helps prevent flea eggs from hatching. Do not let your cat or dog swim for 48 hours after applying Frontline. If you have a heavy flea infestation you’ll need to spray your house with a home flea spray also. Yes, but it’s worth bearing in mind that fipronil alone won’t kill the eggs or larvae in your home.

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